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Unique Major Application Maryland  Form

Unique Major Application Maryland Form

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so the tesometistat is an orally available treatment that's recently been fda approved for follicular lymphoma it's a easy h2 inhibitor and so uh follicular lymphoma is one of those um malignancies in which easy h2 does play a role there are other malignancies such as sarcoma where tesla metastatic has been evaluated um there have also been clinical trials with diffuse large b cell lymphoma but the first indication um here was for follicular lymphoma so uh just over a quarter of patients with follicular lymphoma are found to have easy h2 mutations so there's been a lot of interest to see what the difference might be in response between those patients who have mutated ezh2 versus wild type and there does seem to be a significant difference so this might be you know one of those reasons to do a little bit further characterization of your your patient's um mutational status uh at the time of their of their relapse so with this particular trial this is an open label study of patients with

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