
Partial Gene Deletion of Heart Type Fatty Acid Binding Protein Diabetes Diabetesjournals Form
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People also ask
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What is the function of fatty acid binding proteins?
Also known as fatty acid-binding proteins (FABPs), these are a group of proteins that coordinate lipid trafficking and signalling in cells, and some isoforms are also strongly linked to metabolic and inflammatory pathways.
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What is the function of the heart type fatty acid binding protein?
Heart-type fatty acid–binding protein (H-FABP) is a small cytosolic protein involved in transporting long-chain fatty acids in the myocardium and is released in response to myocardial damage,86 indicating its potential as a sensitive biomarker for acute myocardial infarction (MI).
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What is intestinal type fatty acid binding protein?
Intestinal fatty acid binding protein, also termed FABP2 or I-FABP, is specifically expressed in the small intestine. FABP2 can traffic lipids from the intestinal lumen to enterocytes and bind superfluous fatty acids to maintain a steady pool of fatty acids in the epithelium.
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What is the function of the FABP3 gene?
FABP3 is critical for alpha-Synuclein uptake in dopaminergic neurons, thereby preventing synucleinopathies, including Parkinson's disease. Deficiency of FABP3 protects cardiac myocytes from apoptosis and alleviates cardiac remodeling after myocardial infarction.
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What is the heart type fatty acid binding protein?
Heart-type Fatty Acid-Binding Protein (H-FABP) is a small cytoplasmic protein (15 kDa) released from cardiac myocytes following an ischemic episode.
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What is the fatty acid binding protein family?
Fatty acid-binding proteins (FABPs) are members of the intracellular lipid-binding protein (iLBP) family and are involved in reversibly binding intracellular hydrophobic ligands and trafficking them throughout cellular compartments, including the peroxisomes, mitochondria, endoplasmic reticulum and nucleus.
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What is the function of the fatty acid chain?
Long-chain fatty acids serve two primary functions in animals. As parts of phospholipids and other complex lipids, fatty acids are critical structural components of cellular membranes. As parts of triacylglycerols, fatty acids represent stored energy.
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