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People also ask
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What is the role of the enzyme DNase?
Deoxyribonuclease (DNase) is a class of nuclease enzymes that cleaves the DNA molecule. It breaks the phosphodiester bond formed between two nucleotides of dsDNA or ssDNA, by cleaving either at/on ends or between the nucleic acid strands.
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What does DNase do in protein purification?
The function of nucleases (DNases and RNases) includes the enzymatic breakdown of DNA and RNA and is necessary for numerous research applications. For example, the purification of proteins and specific nucleic acids often requires the digestion of DNA, RNA or both.
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What is the function of the pancreatic deoxyribonuclease?
The DNase in serum and urine is believed to be of pancreatic origin. While it is considered primarily to be a digestive enzyme that functions to break down DNA in the alimentary tract (15, 32, 38) other functions have been suggested including degradation of DNA in apoptosis (45).
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What is the function of the deoxyribonuclease?
Deoxyribonuclease (DNAse) is an enzyme for degrading DNA to fragmentation by catalyzing the hydrolytic cleavage of phosphodiester linkages in the DNA backbone. DNA is degraded during cell death that accompanies a number of diseases.
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What is the effect of adriamycin on DNA RNA and protein synthesis in cell free systems and intact cells?
Apparently, in the cell free system adniamycin is capable of binding to some of the RNA molecules involved in protein synthesis. The preferen tial binding of adriamycin to chromosomal DNA in intact cells may leave only a few molecules of this antibiotic free to bind the RNA involved in protein synthesis.
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What does deoxyribonuclease protein do?
The role of the DNase enzyme in cells includes breaking down extracellular DNA (ecDNA) excreted by apoptosis, necrosis, and neutrophil extracellular traps (NET) of cells to help reduce inflammatory responses that otherwise are elicited.
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