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Wo of the Most Important Challenges Confronting the Nephrology  Form

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yes you know I think um it's difficult to really say you know which patients will or will not develop icpi Ki but I think the fact that we've identified some key risk factors can sort of help oncologists risk stratified and maybe those are patients that um should have more closer monitoring of their kidney function like maybe patients with worse kidney function at Baseline or having a history of the other immunolated Adverse Events those patients may need more closer monitoring of their kidney function um the other issue is the the proton pump inhibitor used you know we know that they are strongly associated with icpi Aki not just in our study but other studies and so perhaps we should be thinking um twice about putting patients um on immunotherapy on proton pump inhibitors and maybe substituting them with H2 blockers

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