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Structure, Spacing, and Phasing of Nucleosomes on Isolated Forms

Structure, Spacing, and Phasing of Nucleosomes on Isolated Forms

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in this video we'll talk about histones histones are highly basic proteins enriched in lysine and Arginine histones can be found in eukaryotic cell nucleus histone forms the nucleosome it interacts with the DNA to form functional unit of the chromatin known as the nucleosome histone has positive charges and the DNA backbone has negative charges due to phosphate group and they interact with each other via electrostatic interaction histone structure is highly conserved there are four basic type of histones h2a 2B H3 and H4 in all of these cases one common theme is the histone fold which is highly conserved across the histones and across different species now the difference lies in the tail length so the n-terminal histone tail is a site for several modifications and the tail length is variable between different different histones and this is an extensive site for different modifications like acetylation phosphorylation methylation ubiquity inhalation just to name a few but question is ho

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