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Structure, Spacing, and Phasing of Nucleosomes on Isolated Forms

Structure, Spacing, and Phasing of Nucleosomes on Isolated Forms

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the dna in the cell is not naked instead its helical strands are wrapped around proteins called histones to form structures called nucleosomes when you have completed this exercise you should understand basic nucleosome and chromosome structure understand the process of nucleosome disassembly and reassembly and understand the importance of histone distribution in the daughter chromatids the human genome contains about three billion base pairs if stretched out such a dna strand would be one meter long in order to fit two copies of this large genome into each human cell the dna is neatly wound into 23 pairs of chromosomes the first step in compacting dna into chromosomes is the assembly of nucleosomes each time the cell divides the dna must be duplicated after the dna is copied the two daughter strands are rapidly reassembled into nucleosomes the old histones are carefully distributed between the two new dna strands and new histones are brought in to fill in the gaps the nucleosome consi

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