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People also ask
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What is the CDBG CV substantial amendment?
Through this amendment, the state will allocate less than three percent of previously unallocated or recaptured CDBG-CV funds to the state to directly support grant recipients to carry out all eligible activities listed in the CV1 and CV2/3 NOFAs and made available pursuant to the FY19 AAP Second Substantial Amendment, ...
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What are the criteria for a substantial amendment?
Amendments to the trial are regarded as “substantial” where they are likely to have a signNow impact on: the safety or physical or mental integrity of the subjects, or the scientific value of the trial, or the conduct or management of the trial, or the quality or safety of any IMP used in the trial.
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What is a substantive amendment?
Substantive Amendment means an amendment other than an Editorial Amendment. It changes the purpose, scope or substantive content of the Policy Instrument.
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What is the difference between a substantial and non-substantial amendment?
Generally, if the changes in the documents are signNow then you have substantial amendment. If you have administrative type of changes - improve wording, consistency, fixing typos, etc. then it is non-substantial amendment.
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What is substantial and non substantial amendment?
An amendment can be substantial or non-substantial depending on the type of change being made. By definition 'A substantial amendment is a change that is likely to have a signNow impact on the safety or physical or mental integrity of the clinical trial subjects, or the scientific value of the clinical trial' [1].
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What is an example of a non-substantial amendment?
Examples of Non-substantial amendments Minor changes to the protocol or other study documentation, e.g. correcting errors, updating contact points, minor clarifications; Updates of the investigator's brochure (unless there is a change to the risk/benefit assessment for the trial);
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