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So RVCL is a disease that begins in middle-age. The disease then is a relentless and progressive dropout of small blood vessels throughout the body. And then these patients get progressively more debilitated And lose mental function, lose physical function and become blind. So it's a progressive relentless disease that leads into death in about five to 10 years. How's it going? Good to see you. How are you? Kim was one of the original three patients in the trial. And we follow her now for a number of years. We know how many lesions she has in her eye. We know how many lesions she has in her brain, where they are. And so what we can do then is start her treatment. And we infuse over a five-day period the drug. It's a chemo therapeutic agent. A cousin of it is used to treat acute leukemia. But here we don't want to kill the cells. What we want to do is make the cells work better. We're giving them just enough we hope that will correct or partially

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