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Exhibitor Brochure FMQAI  Form

Exhibitor Brochure FMQAI Form

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[Music] Tammy Kielian: Hi,   I'm Tammy Kielian at the University of Nebraska  Medical Center, and I'm here to kind of give   an overview of our manuscript that was recently  published in JCI on the topic of staphylococcal   biofilm and its, um, preferential interactions and  programming of, uh, granulocytic MDSCs. So Staph   aureus is a common cause of biofilm infection.  And in the context of this paper we're looking   at prosthetic joint infection. And a biofilm is,  is very, uh, difficult to treat. It's caused by   a collection of bacteria that coalesce into  a, um, heterogeneous community of organisms.   And as such we've shown in prior work from  our group that this actually polarizes the   immune response to an antiinflammatory state  and therefore, uh, prevents clearance of the   bacteria. So granulocytic MDSCs are the cell  type we focused on in this paper. We know that   they represent the abundance, uh, infi

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