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TNF and TNF Receptor Expression and Sensitivity in Human  Form

TNF and TNF Receptor Expression and Sensitivity in Human Form

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well thank you all very much real pleasure to be here I'm going to review some of those discoveries for you and uh tell a little bit about their historical context I think uh all of you would accept that Immunology is very much concerned with infection the immune system arose to cope with infection and it's infection that has claimed more lives from our species and certainly more years of life than anything else I want to talk about that just a little bit at the beginning this is a slide that I got from Jean laurant kasanova and uh it's interesting to look at median survival in different populations over different periods of time in the year 2000 in the United Kingdom it was established as you see here that the median survival time was about 80 years which I think is about what you'd all expect in the very same year in mosambique the situation was quite different and median survival was only 39 years that's a little bit surprising but more surpri

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