Actinic Keratosis and Squamous Cell Carcinoma Global Academy Form

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First off, I think we'll talk about squamous cell carcinoma before coming back to basal cell carcinoma. Squamous cell carcinoma, as you may recall typically is on a spectrum of development or evolution starting with actinic keratosis, then squamous cell carcinoma in situ and then squamous cell carcinoma. Actinic keratosis are described as these discrete dry, sandpapery, skin colored or yellow-brown papules. They're incredibly common, very hard to see just visually until you reach in closely, look closely at the skin and rub your fingers on the lesion and you'll feel that sandpapery lesion especially on the scalp of folks who are balding or bald or on the backs of the hands. One percent of actinic keratosis will evolve into squamous cell carcinoma in situ per year. So, if you got 50 of them, there's a 50% chance that one of those might evolve into squamous cell carcinoma in situ each year. When you've got squamous cell carcinoma in situ especially a background of several of them these w