The Dual Role of Dendritic Cells in the Denise Kirschner University Form

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dendritic cells the key antigen presenting cells of the immune system are generated from progenitors in the bone marrow that migrate into peripheral tissues through the bloodstream there the immature dendritic cells lie in weight for pathogens entering the body through sites of injury for example dendritic cells Express various pattern recognition receptors that can recognize common features of many bacterial and fungal pathogens through these receptors they're able to bind to and phagocytose pathogens when these receptors bind pathogens they activate the dendritic cells which then start to mature in this process they migrate from the tissues and change their behavior to stop phagocytosis and to start expressing immune stimulatory molecules the activated dendritic cells migrate from the tissues into lymphatic vessels where lymphatic fluid drains through lymph nodes carrying the dendritic cells with it T cells migrating through the lymph nodes inspect the dendritic cells for the presenc