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Recommendations for the Use Form
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G-CSF in neutropenia guidelines
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People also ask
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What are the criteria for use of filgrastim?
Filgrastim is indicated for chronic administration to reduce the incidence and duration of sequelae of neutropenia (e.g.‚ fever‚ infections‚ oropharyngeal ulcers) in symptomatic patients with congenital neutropenia‚ cyclic neutropenia‚ or idiopathic neutropenia.
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What is the guideline for G-CSF?
The recommended dose of G-CSF is 10 μg/kg daily for 7–10 days before apheresis, with or without chemotherapy.
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How often do you need a G-CSF injection?
You will need to have a daily course of the injections in the four days leading up to your donation. G-CSF is also given to some patients receiving treatment for cancer. It makes their bone marrow produce white blood cells which have been depleted by chemotherapy, and helps them to fight infections.
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What is the guideline for filgrastim?
The recommended starting dose of filgrastim is 1.0 MU/kg/day (10 mcg/kg/day). The first dose of filgrastim should be administered at least 24 hours following cytotoxic chemotherapy and at least 24 hours after bone marrow infusion.
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What is the indication for G-CSF?
G-CSF is used to treat and prevent neutropenia, especially during cancer treatments. Neutropenia means having a lower-than-normal level of neutrophils. Having neutropenia can make it harder for your body to fight infections. Your healthcare provider may prescribe G-CSF for various reasons.
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When to give G-CSF for neutropenia?
Current guidelines recommend their use when the risk of febrile neutropenia is greater than 20%. GM-CSF (sargramostim) is approved for neutropenia associated with stem cell transplantation.
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When to give Gscf?
G-CSF should not usually be administered less than 24 hours following cytotoxic chemotherapy and is usually started 1-3 days after administration of myelotoxic chemotherapy.
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Why is filgrastim given after chemotherapy?
Filgrastim helps the bone marrow to make new white blood cells. When certain cancer medicines are used to fight cancer cells, they also affect the white blood cells that fight infections. Filgrastim is used to prevent or reduce the risk of infections while you are being treated with cancer medicines.
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