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Exon Junction Complex Subunits Are Required to Splice Drosophila Saturn Med Nyu Form
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People also ask
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What is exon?
An exon is a region of the genome that ends up within an mRNA molecule. Some exons are coding, in that they contain information for making a protein, whereas others are non-coding. Genes in the genome consist of exons and introns.
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What does exon do in DNA?
Exons are coding sections of an RNA transcript, or the DNA encoding it, that are translated into protein. Exons can be separated by intervening sections of DNA that do not code for proteins, known as introns.
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What are introns and exons?
Introns are noncoding sections of an RNA transcript, or the DNA encoding it, that are spliced out before the RNA molecule is translated into a protein. The sections of DNA (or RNA) that code for proteins are called exons.
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What is exon junction complex translation?
The EJC has major influences on translation, surveillance, localization of the spliced mRNA, and m6A methylation. It is first deposited onto mRNA during splicing and is then transported into the cytoplasm. There it plays a major role in post-transcriptional regulation of mRNA.
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What is the exon junction binding protein?
The exon junction complex (EJC) is an RNA-binding protein complex that is assembled and deposited onto mRNAs during splicing. The EJC comprises four core components that bind to not only canonical sites upstream of exon-exon junctions, but also to noncanonical sites at other positions in exons.
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What does the exon junction complex do?
The exon–exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay.
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What is the function of the exon?
An exon in DNA is the coding sequence that will be used to translate the sequences into amino acids, which will then be folded into proteins.
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What are exon-exon junctions?
An exon junction complex (EJC) is a protein complex which forms on a pre-messenger RNA strand at the junction of two exons which have been joined together during RNA splicing. The EJC has major influences on translation, surveillance, localization of the spliced mRNA, and m6A methylation.
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