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hello friends in this video we are going to  discuss about a very common genetic entity that   is down syndrome so down syndrome is a condition  where there are three copies of chromosome 21   okay three copies of chromosome 21. so normally  in our body we have two copies of each of the   chromosomes like chromosome 1 chromosome 2  chromosome 3 and so on okay but if we have   three copies of chromosome 21 that condition  is called trisomy 21 and that is an abnormal   condition which is known as down syndrome okay  so there are some risk factors for down syndrome   so one of them is maternal age as the mother's  age increases the risk of having a baby with   down syndrome also increases so as you can see if  the mother's age is around 20 years the risk of   having a baby with down syndrome is only about one  in fifteen hundred but as the mother's age goes on   progressing so if the mother's age is 45 years  then the risk or incidence of having a baby with  

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