STATS TRANSCRIPTIONAL CONTROL and BIOLOGICAL IMPACT Form
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People also ask
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Why are transcriptional controls important?
For many genes, transcription is the key on/off control point: If a gene is not transcribed in a cell, it can't be used to make a protein in that cell. If a gene does get transcribed, it is likely going to be used to make a protein (expressed). -
What are examples of transcriptional control?
The maltose operon is an example of a positive control of transcription. When maltose is not present in E. coli, no transcription of the maltose genes will occur, and there is no maltose to bind to the maltose activator protein. -
What is STAT3 gene?
The STAT3 protein is active in tissues throughout the body. It plays an important role in the development and function of several body systems and is essential for life. In the immune system, the STAT3 protein transmits signals for the maturation of immune system cells, especially T cells and B cells. -
What is transcriptional control of gene expression describe?
In molecular biology and genetics, transcriptional regulation refers to the mechanism through which a cell controls the transcription (or orchestration) of DNA into RNA. At the transcriptional level, gene expression can be controlled. The amount of mRNA generated by a specific gene in the DNA is regulated. -
What is control of transcription?
As in bacteria, transcription in eukaryotic cells is controlled by proteins that bind to specific regulatory sequences and modulate the activity of RNA polymerase. -
What is transcriptional control in prokaryotes?
A fast and efficient control system is needed, and in prokaryotes, this means that the controls on transcription are simple activators and repressors. For some genes, both may be used for regulation, while for others, only one is needed to change from a default state of expression or non-expression. -
Is STAT a transcription factor?
The signal transducer and activators of transcription (STAT) family of proteins were initially identified as transcription factors that could facilitate the rapid induction of target genes in response to specific extracellular stimuli, including cytokines, growth factors and other agents, through tyrosine ... -
What is STAT in cell biology?
Abstract. Interaction of cytokines with their cognate receptors leads to the activation of latent transcription factors – the signal transducers and activators of transcription (STAT) proteins – whose biological activities ultimately regulate many critical aspects of cell growth, survival and differentiation. -
What is a transcriptional control in biology?
Transcriptional regulation is a critical biological process that allows the cell or an organism to respond to a variety of intra- and extra-cellular signals, to define cell identity during development, to maintain it throughout its lifetime, and to coordinate cellular activity. -
Where does transcriptional control occur?
This type of regulation is not efficient in eukaryotes because transcription occurs in the nucleus while translation occurs in the cytoplasm.
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