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sickle cell disease port for diagnosis and treatment we have discussed before an introduction pathophysiology clinical picture of sickle cell disease now have diagnosed and how to manage sickle cell disease but first let me tell you there is no cure other than stem cell transplant which is a major surgery with a lot of risk most of the time we are talking about management how to reduce symptoms but the ultimate cure is again stem cell transplant or bone marrow transplant but first let me answer the quiz of last time video the most common cause of death in sickle cell disease and children is infection most common cause of death in adults with sickle cell disease is acute chest syndrome the causative organism of meningitis and children strep pneumo is the most common most common cause of organism of bacteremia strep pneumo most common cause of organism of osteomyelitis Salmonella second most common is staph aureus Salmonella has exceeded staph aureus because there is no spleen and Salmon

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