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thanks for joining me for this video lecture on DNA mutations in particular we're going to look at some of the common ways that DNA can be altered and what the results in the final protein product could potentially be so when we think of a mutation we're thinking of a change in the DNA sequence that typically though not always results from mistakes during DNA replication at the DNA level the most common form of mutation is what we call a point mutation a mutation that affects only one position in the DNA sequence there are a couple different types of point mutations there are for example base substitutions where a single nucleotide is replaced and so for example maybe DNA polymerase is supposed to put an A in a particular position and it accidentally puts a G and proofreading doesn't pick it up and so the G gets carried on to the progeny we would call that a base substitution form of a point mutation other point mutations couldn't could include insertion

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