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 YEARLY SUMMARY PATIENT INFORMATION  SCNIR  Severe Chronic Neutropenia 2000-2024

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This video is going to be on the main causes of neutropenia there are many causes of neutropenia but the two most common are inflammation and decreased production, so we're gonna focus on those two causes in this video this slide is going to show inflammatory nature themed PDS okay so with inflammatory neutropenia there is intense inflammation in the tissues and this demand for neutrophils is so great that the neutrophils are entering the tissues and exiting the blood at a much higher rate than the bone marrow can produce and release, so the bone marrow is still working it just can't meet or exceed the demand in the tissues so with inflammatory neutropenia demand exceeds production to help you identify inflammatory neutropenia you look for a left shift which means there will be bands neutrophils and circulation or earlier forms, and you can look for signs of neutrophil toxicity the second cause of neutropenia that I'll talk about is decreased production and that's pretty much what it s

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