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Structure Activity Relationship of Paracetamol PPT Form

Structure Activity Relationship of Paracetamol PPT Form

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Okay. We are still working through our nervous system medications. We will now be talking about analgesics. If you are following along with our flashcards, we are on flashcard number 69. So in this video, we will talk about antipyretics, NSAIDs, and salicylates. Alright. Let's first talk about an antipyretic medication, which is acetaminophen or Tylenol is the brand name. Acetaminophen is used for mild to moderate pain and for a fever. It works by inhibiting prostaglandin synthesis in the CNS. It doesn't have many side effects, but the one important side effect that it does have is hepatotoxicity with large doses. So it actually carries a black-box warning because of this risk for hepatotoxicity. So it's going to be really important that your patient not exceed 4 grams a day of acetaminophen. And keep in mind that many over-the-counter products, like for colds, do contain acetaminophen as well. So if your patient is using acetaminophen for pain and also using a

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