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Renal Failure and Cirrhosis Nejm PDF Form

Renal Failure and Cirrhosis Nejm PDF Form

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The prevalence of chronic kidney disease is increasing worldwide, but the long-term risk of progression of childhood kidney disease has been unclear. In a nationwide, population-based, historical cohort study in Israel, investigators reviewed the baseline medical examinations of over 1.5 million adolescents before compulsory military service between 1967 and 1997. Inclusion in the cohort required normal kidney function and normal blood pressure in adolescence, irrespective of a history of childhood kidney disease, categorized as congenital anomalies of the kidney and urinary tract, pyelonephritis, and glomerular disease. The adolescent cohort data were linked to the Israeli end-stage renal disease registry, and Cox proportional hazards models estimated the hazard ratios for end-stage renal disease associated with a history of childhood kidney disease. During a mean of 30 years’ of follow-up, 2,490 people (or approximately 0.2% of the cohort) developed end-stage renal disease. Multiva

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