
Multiple Forms of Phosphoinositide Specific Phospholipase C of Ncbi Nlm Nih
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People also ask
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What are the subtypes of phospholipase C?
There are thirteen kinds of mammalian phospholipase C that are classified into six isotypes (β, γ, δ, ε, ζ, η) ing to structure. Each PLC has unique and overlapping controls over expression and subcellular distribution. However, PLC is not limited to mammals, and is present in bacteria and Chromadorea as well.
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How many isotypes of phospholipase C are known?
The phospholipase C family consists of 13 isoenzymes split between six subfamilies, PLC-δ (1,3 & 4), -β(1-4), -γ(1,2), -ε, -ζ, and the recently discovered -η(1,2) isoform.
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What are the isoforms of phospholipase C?
Phospholipase C (PLC) There are also multiple isoforms of PLC, comprising six family members: PLCβ (four subtypes), PLC-γ, PLC-δ, PLC-ɛ, PLC-δ and PLC-η.
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What is phosphoinositide specific phospholipase C?
The phosphatidylinositol-specific phospholipase C is sensitive to nutrient concentration (glucose) and other secretagogues in the beta cells. The PLC serves as modulator in amplifying concentration of cytosolic calcium in the beta cells.
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What are the different types of phospholipase C?
There are thirteen kinds of mammalian phospholipase C that are classified into six isotypes (β, γ, δ, ε, ζ, η) ing to structure. Each PLC has unique and overlapping controls over expression and subcellular distribution.
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What are the 4 types of phospholipases?
The major categories of phospholipase are phospholipases A (PLA), phospholipases B (PLB), phospholipases C (PLC), and phospholipases D (PLD). PLA and PLB both have a specific potential of hydrolytic cleavage of phospholipid's acyl ester bond at site number 1 or 2 (sn-1 or sn-2).
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