License Certificate Biacore Form

Instructions and help about License Certificate Biacore

vehicle systems monitor the interaction between two molecules the ligand is attached to the sensor surface and the analyte free in solution there are different ways to attach the molecule to the surface the most common procedure is direct covalent coupling using reactive groups on the ligand for immobilization covalent immobilization fixes the molecule permanently on the surface often with a heterogeneous orientation capture based coupling is another common approach and it's used when ligand is unstable or difficult to immobilize or regenerate and hydrophobic attachment is used for work with lipid bilayers or liposomes there are a range of general purpose sensor chips used for covalent coupling chemistry the general steps involved in immobilizing ligands are the same for essentially all covalent methods vehicle systems offer similar support for thiol malamide and aldehyde coupling the most common coupling procedure amine coupling introduces n hydroxy succinamide esters to the surface m