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[Music] so today I'm going to tell you a little bit about the interesting side project in in the lab that mainly was done by Ivan gando and and Manuel and this is how we came up actually through a collaboration with the uh Tom Cardozo laboratory we came up with a compound that that opens KDP channels and I just wanted to tell you the story and so Colin has made my life really easy today because he already introduced the ATP sensitive protesting Channel and I don't have to do that and he mentioned to you that unlike other potassium channels where you've got six or four transmembrane domains these are inward rectifier potassium Channels with only two transmembrane and these are the different subframes a very diverse group of of proteins so the KDP channel is basically forming to this category over here and after inward rectifier potassium channels there's something like 15 or something lost count and they fall really into four different groups the kir3s co

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