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Peanut Allergy Uiowa  Form

Peanut Allergy Uiowa Form

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no treatment for peanut allergy is approved for children younger than four years of age yet immune modulation may be more effective at younger ages treatment with patch-based immunotherapy has shown efficacy and safety in older children in this phase 3 multi-center double-blind trial 362 children one to three years of age with confirmed peanut allergy were assigned in a two to one ratio to use a skin patch containing 250 micrograms of peanut protein or a placebo patch daily for 12 months the primary endpoint was desensitization to oral peanut challenge at 12 months defined as requiring at least a thousand milligrams of peanut protein to illicit allergy symptoms in children with a baseline eliciting dose of greater than 10 milligrams or requiring at least 300 milligrams for those with a baseline eliciting dose of 10 milligrams or less significantly more of the intervention group than the placebo group became desensitized key secondary endpoints also favored the intervention group includ

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