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 Dr Eric J Schenkel MD ReviewsBethlehem, PAVitals Com 2019-2025

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hello I'm Cody Martin a PhD student in the on at the ramen Lab at the University of Wisconsin-Madison and I'm focused on developing bioinformatics software and tools to advance our understanding of how viruses affect microbiomes today I will be talking about a database I developed called Fame DB to catalog auxiliary metabolic genes and bacterial viruses viruses infecting bacteria also known as phage have been found to encode auxiliary metabolic genes or amgs that they can use to manipulate host metabolism and modify host behaviors all for the benefit of the phage and the upper right is an example diagram of a phage increasing flux through a sulfur metabolic pathway in which the phage encodes two amgs that are known to be rate limiting in this pathway the ultimate effect that this has is that more ATP is generated for the benefit of the phage other examples of functions that phage have been found to manipulate include virulence and toxin production other biogeochemical c

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