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Pld Pi 001 2  Form

Pld Pi 001 2 Form

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so 95752 is administered intravenously every three weeks and there was a dose escalation portion followed by dose expansion cohorts the data we presented was focused on the dose escalation and the 2000 milligram dose expansion cohort in total there were 86 patients including 61 from dose escalation 25 from the dose expansion the median age was 60 most patients were male the most common tumor types were kidney cancer and lung cancer medi5752 was tolerated uh reasonably well about thirty eight point four percent of patients had grade three or four adverse uh adverse events related to media five seven five two and thirty one percent of patients discontinued treatment due to treatment-related adverse events however there were only three dlts or dose-limiting toxicities observed and as such a maximum tolerated ghost was not reached the most common side effects were rash um hepatic events and hypothyroidism and those very low rates of colitis observed which is very unusual for drugs to targe

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