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 2570 BCD 1 08 DOC 2008

2008-2025 Form

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keynote 091 is one of these two trials which have been today presented which look at the addition of immunotherapy after standard of care treatment of stage one B to stage 3 and osmosyl and cancer the ID is patients on the go and benefit from a complete resection of the tumor they receive chemotherapy in in pastoral it was optional maximum of four Cycles but after that they are randomized between one year of pembrolizumab or Placebo okay this trial was looking at two dual core primary endpoints so means that if one of Twin Ponds is positive the trial is positive by statistical design so the first one was this is free survival in this whole population ITT and the secondary the second dual primary endpoint was the DFS in high pdl1 the ones with the TPS score are more than 50 percent so while the whole population was statistically significant in terms of prolonging the DFS with a significant p-value so something which is Paradigm changing the subgroup which is supposed to benefit the most

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