Uncoupling Protein 1 Expression and High Fat Diets Ajpregu Physiology Form

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welcome back in this video we're gonna go over a concept called uncoupling enzymes or uncoupling proteins so first of all let's answer the question what is a coupling protein in the context of the respiratory chain coupling proteins are coupling enzymes are enzymes that move hydrogen ions from the inner membrane space into the matrix and couple that movement with a with the synthesis of ATP obviously the only example of that is ATP synthase okay remember from the electron transport chain the three complexes one three and four pump protons actively from the matrix into the inner membrane space giving a very high concentration of protons in the inner membrane space and a relatively low concentration in the matrix so there is a tendency both by concentration and electric forces that these protons would like to move back into the matrix they're higher in energy higher and potential energy in the inner membrane space and the spontaneous movement would be to move back into the matrix okay gi