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There Are Three Distinct Forms of Bombesin Jbc
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People also ask
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What is the function of the bombesin?
Bombesin is a 14-amino acid peptide originally isolated from the skin of the European fire-bellied toad (Bombina bombina) by Vittorio Erspamer et al. and named after its source. It has two known homologs in mammals called neuromedin B and gastrin-releasing peptide. It stimulates gastrin release from G cells. -
What is the neurotransmitter bombesin?
Bombesin (BBS) is a 14-amino-acid peptide first isolated from the skin of the frog, Bombina bombina, in 1970 by Erspamer. Injection of exogenous BBS in rat and other mammals reduces food intake, and in the rat it triggers a sequence of behaviors that accompany satiation. -
What is the bombesin family of peptides?
The bombesin-like peptides can be divided into three subfamilies—the GRP family, the NMB family, and the bombesin-related peptide (BRP) family (Fig. 1). At present, the BRP subfamily has been characterized only in amphibians but also likely occurs in mammals. -
What is the name of the gene bombesin?
BRS3 (Bombesin Receptor Subtype 3) is a Protein Coding gene. Diseases associated with BRS3 include Brugada Syndrome 4 and Lung Cancer. Among its related pathways are Class A/1 (Rhodopsin-like receptors) and GPCR downstream signalling. -
What is the name of the bombesin also known as?
Gastrin-releasing peptide receptor ([GRPR] also known as bombesin receptor 2 [BRS1, BB2, BBR-2]). GRPR is expressed in the pancreas and at lower levels in the colon, breast, prostate, and skin. -
What is another name for bombesin?
Gastrin-releasing peptide receptor ([GRPR] also known as bombesin receptor 2 [BRS1, BB2, BBR-2]). GRPR is expressed in the pancreas and at lower levels in the colon, breast, prostate, and skin.
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