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hi I'm air Jorgensen I'm from the University of Utah what I'd like to talk today is the recycling of synaptic vesicles so before we get started I'd like to tell you a bit about synaptic transmission so the way it works is that there is a cell body that can be very far away from the synaptic bouton an axon that extends all the way to this synaptic bouton and that could be about a meter long so the synaptic bouton needs to act as an independent organelle so the way this works is that there are synaptic vesicles are filled with neurotransmitter molecules and then these molecules these synaptic vesicles are then docked at the membrane and so the way synaptic transmission works is that when there's a calcium influx the vesicles then are released the vesicle fuses with the plasma membrane and releases the neurotransmitter onto the receptors shown here so by doing that you lose the synaptic vesicle membrane and you lose the synaptic vesicle proteins and

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