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Maps Volume Xiv Number 2 Rites of Passage Kids and Psychedelics  Form

Maps Volume Xiv Number 2 Rites of Passage Kids and Psychedelics Form

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we also spent a lot of time looking at the side chain so this is dom but we did it with the dob analog and we played with the side chain we made five membered rings six membered rings incorporated into big rings etc so here was a cyclopropyl up here we made a cyclopropyl we made a cycle butyl made a five-membered ring here then we made a four-membered ring and this is over a period of 25 years we finally got this is tcb2 it's actually used it's supplied by a commercial company now as an agonist for the 2a receptor it's not a controlled substance but it's too expensive to buy for recreational purposes anyway so we mapped so we mapped out the orientation of the methoxys and we've already mapped out the orientation of the side dune so if you look at this side chain comes out comes up and projects over and this is actually it's two stereoisomers i've shown the active isomer you could have the other isomer so we know which one we did x-ray crystallography we know which one binds so we know

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