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Comparison of Long and Short Forms of the Prolactin Receptor on

Comparison of Long and Short Forms of the Prolactin Receptor on

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prolactin is the major hormone responsible for milk production and also participates in the development of the breasts prolactin is synthesized by lactotrophs which represent approximately 15 percent of the tissue in the anterior lobe of the pituitary gland in non-pregnant females and in males blood levels of prolactin are low so what makes these people have low prolactin levels in their blood the answer is dopamine secretion by the hypothalamus secreted dopamine binds to specific receptors on the lactotrophs and inhibits the release of prolactin however during pregnancy and lactation blood levels of prolactin increase there are two reasons that increase the prolactin level in the blood during these periods first one is during pregnancy and lactation hypothalamus secretes thyrotropin releasing hormone also called prolactin releasing hormone which stimulate prolactin release and the second one is suckling which is the most powerful stimulus for prolactin release stimulation of the sends

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