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Comparison of Long and Short Forms of the Prolactin Receptor on
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People also ask
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What type of receptor signaling does prolactin use?
Prolactin functions by binding cell-surface expressed prolactin receptor, initiating signaling cascades, primarily utilizing Janus kinase-signal transducer and activator of transcription (JAK-STAT). Pathway disruption has been implicated in tumorigenesis, reproductive abnormalities, and diabetes. The prolactin receptor: Diverse and emerging roles in pathophysiology nih.gov https://.ncbi.nlm.nih.gov › articles › PMC5685068 nih.gov https://.ncbi.nlm.nih.gov › articles › PMC5685068 -
What is prolactin receptor regulation?
PRL receptors are expressed in breast tissue and in many other tissues including pituitary, liver, adrenal cortex, kidneys, prostate, ovary, testes, intestine, epidermis, pancreatic islets, lung, myocardium, brain, and lymphocytes. Regulation of milk production occurs via a cascade of intracellular events. Prolactin Receptor - an overview | ScienceDirect Topics sciencedirect.com https://.sciencedirect.com › topics › prolactin-receptor sciencedirect.com https://.sciencedirect.com › topics › prolactin-receptor -
What is the prolactin cytokine receptor?
The prolactin receptor is a member of the cytokine receptors that lacks an intrinsic kinase domain but possesses a JAK2-associating region. Upon prolactin stimulation, the prolactin receptor transduces signals through the activation of JAK2, leading to the phosphorylation of JAK2. Prolactin Receptor - an overview | ScienceDirect Topics ScienceDirect.com https://.sciencedirect.com › topics › prolactin-receptor ScienceDirect.com https://.sciencedirect.com › topics › prolactin-receptor -
What is the short form of prolactin?
The short form of the prolactin (PRL) receptor silences PRL induction of the beta-casein gene promoter. Mol Endocrinol. The short form of the prolactin (PRL) receptor silences PRL ... - PubMed nih.gov https://pubmed.ncbi.nlm.nih.gov › ... nih.gov https://pubmed.ncbi.nlm.nih.gov › ...
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