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OAI X Ray Manual Osteoarthritis Initiative  Form

OAI X Ray Manual Osteoarthritis Initiative Form

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The NIH Osteoarthritis Initiative Osteoarthritis, the most common form of arthritis, is a joint disease marked by the gradual loss of cartilage that cushions and protects the bones, abnormal bone growth around the joint, and other joint changes that cause pain and disability. An estimated 27 million Americans age 25 and older have osteoarthritis, and the knee is among the most commonly affected joints. There are currently no treatments - other than surgical joint replacement - that change the course of the disease, and clinical trials for prospective therapies are long, difficult and expensive. Current methods of evaluating osteoarthritis disease progression, including X-rays and blood tests, are not accurate enough to be used in clinical trials of potential treatments. Scientists, health care providers and drug companies need biochemical and imaging markers of how osteoarthritis progresses to better diagnose, monitor and treat the disease. In response to this need, the NIH Osteoarthri

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