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Appendix K Winthrop University Form

Appendix K Winthrop University Form

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first to the stage I would like to invite Joe sassani to talk about el COSO Rx thanks Erica thank you for the opportunity to introduce naltrexone for topokki use in the treatment of early stage diabetic foot ulcers we believe that now trek sown for diabetic ulcers is AD risk high potential commercial opportunity in part because this is a repurpose for an established drug there's a proof for systemic administration for drug and alcohol abuse we have a novel technology strong intellectual property as I'll show you and compelling up economics because this is a repurposed drug it should have a simplified regulatory pathway and reduced risk etc unfortunately there's a global diabetes epidemic even in the United States there are 23 million diabetics of whom 2.3 million have foot ulcers fortunately about 70 percent have early stage foot ulcers as you see in that top picture we want to prevent them for progressing to more serious officers and even amputations we think w

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