Xywav Prescription 2020-2025 Form
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People also ask
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What is the street name for XYWAV?
Xywav has a high potential for abuse and contains sodium oxybate which is also known as the street name of GHB, a known street drug of abuse. However, there are differences in purity between GHB which is sold on the street, and GHB which is contained in Xywav.
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Why is Xyrem used for narcolepsy?
Narcolepsy is a sleep disorder that is characterized by excessive daytime sleepiness. Xyrem (sodium oxybate) is the sodium salt of gamma-hydroxybutyrate (GHB) which is a central nervous system (CNS) depressant. CNS depressants slow down brain activity, which makes them useful for treating sleep disorders.
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What is the difference between Xyrem and XYWAV?
Both XYWAV and XYREM contain oxybate as their active ingredient, but XYWAV is a lower-sodium formulation. At the maximum recommended 9‑g nightly dose, XYWAV has 131 mg of sodium vs ~1640 mg with XYREM, a high‑sodium oxybate. This means that XYWAV has ~1509 mg less sodium per night than XYREM at the 9-g nightly dose.
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Is Xyrem still prescribed?
Specifically, under both the Xyrem REMS and the generic sodium oxybate REMS, sodium oxybate can be prescribed only by a certified prescriber, and dispensed only to an enrolled patient by a certified pharmacy. Only a certified pharmacy that ships directly to patients can dispense sodium oxybate.
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What medical condition is treated by XYWAV?
Xywav is used to treat certain sleep disorders. These include idiopathic hypersomnia and narcolepsy symptoms of excessive daytime sleepiness and cataplexy. Xywav belongs to a class of drugs called central nervous system (CNS) depressants.
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What are the benefits of XYWAV?
XYWAV, taken at night, is thought to work during sleep to help improve 2 common symptoms of narcolepsy during the day. XYWAV is the first and only low-sodium oxybate approved by the FDA for treating cataplexy and/or EDS in people ages 7 years and older with narcolepsy.
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What pharmacy dispenses XYWAV?
XYWAV and XYREM will be dispensed only by the REMS Certified Pharmacy.
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What are the alternatives to Xyrem?
Drug Medical Necessity Armodafinil (Nuvigil) Mixed oxybate salts (Xywav) Modafinil (Provigil) Pitolisant (Wakix) Sodium oxybate (Lumryz) Sodium oxybate (Xyrem) Solriamfetol (Sunosi) Anti-narcolepsy agents may be considered medically necessary in patients who meet the criteria described in the clinical policy below.
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