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our question was why Kansas distributed of an enum across the body both in time and space and so we set out to understand when there were some fundamental aspects of cells wherever they were in organs and whether those properties that most cells had a requirement MacAlister for so the first thing we did is both in near things and in adults we looked in animals to see what was the function of a particular population of cells that were labeled with a prominent long gene we used Kree lineage tracing that's a way that you can actually just look at both in initial styles themselves and all their progeny over the life at the end to understand the nerve cells proliferating throughout life whether they repaired and regenerated the author and how much of the organ at the end of the day they actually contributed to as well as look at properties such as what the progeny of those cells were did they give rise to mature cell types in each organ and then in parallel to that we targeted those

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