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Proliferation of Stem Cells Which Form, in Se Quence Ncbi Nlm Nih

Proliferation of Stem Cells Which Form, in Se Quence Ncbi Nlm Nih

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hello my name is Florian Merkel I am a principal investigator at the University of Cambridge today I'll be talking about disease modeling with human pluripotent stem cells and I'll talk about my personal interest which is disease modeling of obesity and via that framework I'll talk about general principles of disease modeling and some of the pitfalls that can occur when culturing stem cells and when performing gene editing so as a general principle one can model human diseases in vitro by the case-control method where one could for example take a series of control patients and patients affected with a particular disease derive induced pluripotent stem cells from them and differentiate them into a cell type of interest that's affected in disease for example neurons if you're studying neurological diseases and then if you want is measuring a phenotype that's associated with disease since these are unrelated patients with diverse genetic bac

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