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Mckee's Pathology of the Skin PDF  Form

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so this is an example of acryl skin skin on the palm or sole and you can tell that because it's got a very thick corneal layer here at the top and it's got that stratum lucidum that we talked about previously and the reason i'm showing this this is actually not normal skin this is skin that's involved by contact dermatitis like you get if you touch poison ivy and there's some extra white space up in the surface here that's making a little blister and there's some of this stuff that's called perikeratosis we can go closer and look see normally you don't have nuclei left in the corneal layer but when skin gets irritated and starts growing quickly the nuclei get retained we talked a little bit about that earlier the granular layer kind of goes away or gets diminished and then perikeratosis the presence of nuclei in the corneal layer shows up and so that's a sign that the skin's abnormal that's

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