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 Maryland Dr 057 2018

Maryland Dr 057 2018-2025 Form

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[Music] kino 57 aimed to test Pemberley zermatt which is a pd-1 antibody in a specific population of patients with non-muscle invasive bladder cancer and these are patients with high-risk disease that have received BCG in the past which is an intra vesicle immunotherapy and then are now considered unresponsive to BCG therapy this population historically is actually treated with radical cystectomy which means surgical removal of the bladder and the reason we do this is because unfortunately BCG unresponsive disease the natural history is to progress to muscle invasive and potentially metastatic disease and radical cystectomy historically has been felt to be the only curative therapy for these patients it's in this context that Pember lism AB was tested hopefully as a means to achieve responses in the bladder and hopefully help patients preserve their bladders next steps for this trial are obviously to follow up these patients who have achieved a CR and truly see how long and dur

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