
The High Mobility Group Protein HMG IY Can Stimulate or Inhibit Pnas Form
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People also ask
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What is the function of the HMG protein?
HMG proteins play important roles in remodeling the assembly of chromatin and regulating gene transcription in higher eukaryotic cells by distorting, bending or modifying the structure of DNA, which forms complexes with histones and transcription factors [1, 3, 4].
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What is the role of HMG proteins in eukaryotic gene regulation?
The binding sites of these proteins on nucleosomes overlap the binding site of histone H1, and HMG-14 and HMG-17 appear to stimulate transcription by altering the interaction of histone H1 with nucleosomes to maintain a decondensed chromatin structure that facilitates transcription through a nucleosome template.
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What do eukaryotes use to regulate gene expression?
To regulate transcription, both prokaryotes and eukaryotes rely on proteins that act as either activators that “turn on” gene expression or repressors that “turn off” gene expression. Repressors are more common in prokaryotes than they are in eukaryotes.
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What are the roles of histone proteins with regard to eukaryotic gene expression and regulation?
Answer and Explanation: Histone proteins help to bundle DNA into chromosomes by wrapping it around the eight histones. Histone alterations play a role in many biological processes, including upregulation and deactivation, chromosomal packaging, and DNA damage and repair.
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What is the function of the HMG protein?
HMG proteins play important roles in remodeling the assembly of chromatin and regulating gene transcription in higher eukaryotic cells by distorting, bending or modifying the structure of DNA, which forms complexes with histones and transcription factors [1, 3, 4].
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What proteins are involved in eukaryotic gene regulation?
In eukaryotic cells, helix-turn-helix proteins include the homeodomain proteins, which play critical roles in the regulation of gene expression during embryonic development. The genes encoding these proteins were first discovered as developmental mutants in Drosophila.
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