Authentication
Support for email, SMS, knowledge-based checks, and multi-factor options to verify signer identity and meet regulatory authentication expectations.
Online signatures reduce paper handling, improve record accuracy, and create searchable audit trails that align with regulatory expectations for traceability and documentation retention.
A Clinical Coordinator uses online signatures to obtain and record informed consent and to update participant contact records. They rely on integrated workflows to tie signed consent forms directly to study contact lists and to ensure materials are archived under study identifiers for audits.
A Compliance Manager configures retention rules, verifies audit trails, and confirms signature authentication meets ESIGN and HIPAA expectations. They review signed documents and contact metadata to support inspections and maintain evidence of authorization and chain of custody.
Clinical, quality, and administrative teams use online signatures to streamline approvals tied to contacts and organization records.
These users benefit from centralized record linking, searchable archives, and consistent workflows that reduce administrative burden.
Support for email, SMS, knowledge-based checks, and multi-factor options to verify signer identity and meet regulatory authentication expectations.
Comprehensive, time-stamped logs that record signer actions, IP addresses, and document events to support inspections and legal defensibility.
Reusable document templates with pre-placed fields reduce errors and standardize agreements across sites and vendors for consistent record capture.
APIs and prebuilt connectors enable synchronization with CRMs, EDCs, and cloud storage to maintain a single source of truth for contacts.
Workflow rules and reminders automate routing, escalate overdue signatures, and update contact records upon completion.
Configurable retention policies and archival options align stored signed documents with compliance and organizational record schedules.
Bi-directional exports and imports let teams prepare documents in Google Docs, push them into signature workflows, and capture completed copies back into the document repository while preserving contact metadata and version history.
Connectors for CRM systems synchronize contact and organization records so signed agreements automatically attach to the correct customer or site record and update status fields for downstream processes.
Automated archiving to Dropbox or preferred cloud storage stores signed documents in designated folders with naming conventions tied to contact identifiers and study codes.
Template libraries enable standardized forms with pre-mapped fields, conditional logic, and signature blocks to ensure consistent capture across studies and vendor contracts.
| Feature | Configuration |
|---|---|
| Reminder Frequency | 48 hours |
| Signature Expiry | 90 days |
| Auto-archive Rule | On completion |
| Contact Update Trigger | Signed document |
| Retention Policy | 7 years |
A sponsor digitized site agreements to reduce start-up time and centralized investigator contact records for study teams
Resulting in faster site activation and clearer investigator records for audits.
A clinical team implemented electronic informed consent linked to participant contact metadata to streamline follow-up workflows
Resulting in compliant consent capture that simplifies monitoring and regulatory review.
| Provider | signNow (Recommended) | DocuSign | Adobe Acrobat Sign |
|---|---|---|---|
| HIPAA Compliance | |||
| Bulk Send | |||
| API Access | |||
| Audit Trail Detail | Full | Full | Full |
Retain for study-required duration.
Store for contract life plus six years.
Maintain immutable logs long-term.
Annually review for accuracy.
Apply secure deletion after retention.
| Provider | signNow (Featured) | DocuSign | Adobe Acrobat Sign | HelloSign | OneSpan Sign |
|---|---|---|---|---|---|
| Pricing Model | Per-user monthly or volume | Per-user monthly | Per-user monthly | Per-user monthly | License or per-user |
| Free Tier | Limited free trial | Limited trial | Limited trial | Limited free tier | Trial available |
| Starting Price | Approx. $8 per user/month | Approx. $10 per user/month | Approx. $12 per user/month | Approx. $13 per user/month | Varies by deployment |
| API Access | Included in plans | Available with plans | Available with plans | Available | Enterprise focused |
| Enterprise Support | Standard SLAs and onboarding | Advanced enterprise SLAs | Enterprise SLAs and services | Business support | Enterprise services |