NIH MD/PhD Partnership Training Program FAQs
Below are answers to some of the most frequently asked questions about the NIH
Intramural MD/PhD Partnership Program. Please contact us if your particular question is
not answered here or on our website.
A) General questions about combined MD/PhD Training
Is MD/PhD training right for me? Obtaining combined MD/PHD degree training is a
preferred training pathway for students who are committed to careers combining
biomedical research with the practice of clinical medicine. Obtaining the intensive
mentored training of a Ph.D. and seeing a scientific project from start to finish, while still
at a student level, builds a good foundation for future independent research. Medical
school training that usually ‘book-ends’ the Ph.D. training fosters thinking that combines
the knowledge base of clinical medicine with the investigatory skills of a Ph.D.
researcher. The Medical Scientist Training Program (MSTP), an NIH-sponsored training
program administered by the National Institute of General Medical Sciences (NIGMS) at
42 U.S. medical schools, provides funding for MD/PhD training to 41 U.S. medical
schools which allows these schools to offer students full tuition waivers and a Ph.D.-level
stipend. Individual medical schools also offer equivalent MD/PhD training programs
outside of the MSTP. In total about 500 new students begin MD/PhD training each year
nationwide. MD/PhD-trained investigators have been extremely successful in biomedical
research compared with M.D.-trained peers. Although they make up only 3% of medical
school graduates, MD/PhD-trained investigators hold 30% of NIH grant funding given to
physician-researchers. MD/PhD’s have a slight advantage in obtaining research grants
over Ph.D.-trained peers.
MD/PhD training is definitely not for everyone. If you plan to be a lab-based researcher,
even if you study mechanisms of human disease, obtaining a PhD in a field of biomedical
research may be a better option, and there are increasing opportunities for students in
PhD training to obtain special competency in translational research. If you plan to do
primarily clinically-based research, a Master’s degree in public heath or epidemiology
may be a better option for you. This is a long (seven to eight year) training pathway, and
the financial benefits of tuition and stipend support during medical school fall far short of
what one can earn in three to four years of clinical practice that one would give up to do
PhD training.
See our resources and links pages for more information about this topic.
What do MD/PhD’s do after graduating? Most MD/PhD trainees enter clinical
residency training after completing their degrees, and have gone into every field of
medicine, with the largest proportion training in Medical and Pediatric subspecialties,
Pathology, and Neurology. Training in procedure-oriented medical subspecialties and
surgical subspecialties is possible, although this carries with it the extra challenge of
maintaining competency in complex medical procedures while running a research lab.
MD/PhD trained physicians are also in demand by the pharmaceutical industry as experts
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in translating basic discoveries into new therapeutics. The next research experience after
MD/PhD training usually occurs during subspecialty fellowship in the medical specialties
or during the research years of longer surgical residency training programs. A number of
academic institutions have ‘physician-scientist’ training tracks in their residency and
fellowship training programs tailored for the interests of MD/PhD graduates.
Graduates of the NIH MD/PhD partnership program have followed these trends,
obtaining residencies and fellowships at top academically oriented clinical training
programs such as Memorial Sloan-Kettering Cancer Center, Boston Children’s Hospital,
University of California San Francisco.
B) Questions about applying to the NIH MD/PhD partnership training program
Is the NIH MD/PhD partnership a ‘stand-alone’ MD/PhD training program? No. The
NIH Intramural MD/PHD partnership training program coordinates training, activities
and funding for MD/PhD students who conduct research in the intramural research
program of the NIH in partnership with U.S. medical schools. Students earn the Ph.D.
degree through Individual Partnerships with their medical school or through one of the
sixteen NIH Institutional Partnerships. An NIH scientist serves as your mentor or comentor for the Ph.D. portion of your training. The MSTP program of your medical
school and the admissions committee of the NIH intramural MD/PHD partnership must
independently grant admission and the financial support to pursue this training pathway.
Since the standards for admission are similar, concurrent admission is quite common. The
NIH GPP will work with your medical school and its MSTP to make sure the details of
this program are accurately communicated.
How hard is it to get in? Admission standards for the MSTP funding portion of the
program are similar to those at MD/PHD programs nationwide, where accepted
applicants have average MCAT scores of 35 and a college GPA of 3.7. Research
experience is taken into account, and applicants with particularly strong lab research
credentials whose test scores and GPA are below the averages above are often admitted.
Each GPP program has its own admissions criteria, with varying levels of
competitiveness. Our current admission goals are to admit four students per year in Track
1 of the MD/PhD program to the NIH Oxford-Cambridge Scholars Ph.D. program.
Students applying from medical school for Track 2 of the MD/PhD program are admitted
within the goals of each Ph.D. program. The NIH Oxford-Cambridge program is
currently the largest GPP, admitting 12 new students per year in addition to the four
students admitted through track 1 of the MD/PhD program, and has admissions standards
similar to the MD/PhD partnership. Students holding Scholarships that pay tuition to UK
Universities (e.g. Rhodes, Marshall, Churchill, NSF) are admitted to the OxfordCambridge program in addition to the students above, provided they fulfill the
admissions criteria of the programs.
Do I need to be a U.S. citizen to participate in this program? Yes, you do need to be a
U.S. citizen or permanent resident to participate in the MSTP-funded portion of the
program with U.S. medical schools. Most institutional GPP Ph.D. partnerships do require
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this as well, although there are some of which are open to international students, such as
the NIH-Wellcome Ph.D. studentships for study in the UK. See the list of NIH
institutional partnerships for more information.
What are the benefits of participating in the NIH Intramural MD/PhD Partnership
program? GPP Students enrolled in combined degree training will receive the enhanced
curriculum offered to MD/PhD students at their medical school, which often include
coursework and seminars designed for combined degree trainees, as well as modified
clinical rotation requirements. At NIH a number of activities have been set up for
combined-degree trainees. Students accepted to MSTP-funded MD/PhD programs and
the NIH Intramural MD/PhD Partnership will receive tuition and stipend benefits in most
cases equivalent to traditional MD/PhD students, which involves full tuition waiver and a
stipend similar to that of Ph.D. trainees for the duration of MD/PhD training.
Which MD/PHD partnership training track is right for me? Track 1 is the closest
training track to the traditional MD/PhD training programs, where 1 ½ to 2 years of preclinical training is accomplished before starting in the lab full time. Because less than two
years elapse between the completion of PhD research and clinical residency training, this
training pathway has the advantage of minimizing the time away from research between
the Ph.D. and post-doctoral training. Track 2 is for students currently enrolled in medical
school or at NIH in ‘year-out’ programs from medical school. Once accepted, students’
training in this pathway would be similar to Track 1. Track 3 (Ph.D. first) is a special
pathway for students currently in GPP training with at least one year of graduate training
remaining. Track 3 is also appropriate for students who must start training with the Ph.D.
phase due to a non-deferrable scholarship such as the Rhodes or Marshall programs.
Students in post-baccalaureate training in NIH labs should select Track 3 only if they
would like to stay in their current lab and they and their mentor feel that the research
would suffer if interrupted for medical school training. Students in Track 3 generally
finish the bulk of their Ph.D. research before medical school and are then required to
have a research mentor and perform additional research during the medical school years.
Which NIH Ph.D. partnerships are best for MD/PhD students? Students can combine
MD training with any of the NIH institutional partnerships or individual partnerships.
Typically students arrange an individual Ph.D. partnership with the Ph.D. granted by a
department at the student’s medical school or enroll in an institutional partnership with
fewer Ph.D. course requirements. The programs granting a European D.Phil. (Karolinska,
University College London, Oxford, and Cambridge) are highly compatible with medical
school due to their streamlined structure and minimal coursework requirements.
Discipline-specific Institutional NIH Graduate Partnerships at medical schools such at
University of Pennsylvania (Immunology), Epidemiology (Yale University)
Neuroscience (Brown University), and Bioinformatics (Boston University), may also be
appropriate, especially for students doing their M.D. training at these institutions. See the
list of partnerships on the NIH Office of Intramural Training and Education (OITE) web
site for more information about these partnerships.
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Are there any GPP programs that are not compatible with MD/PHD training?
The Johns Hopkins University - Cell, Molecular, Developmental Biology & Biophysics
GPP is a partnership with an Arts and Sciences Ph.D. program with a heavy emphasis on
teaching and one year of required lab rotations. For this reason we do not feel this
program is appropriate for MD/PhD students. The other partnerships with Johns Hopkins
school of public heath for biostatistics and epidemiology are compatible.
Can I arrange an individual agreement between a Ph.D. program and the NIH
MD/PhD Partnership?
Yes that is possible, most often with a Ph.D. program from the students’ medical school
when a student comes to NIH after completing the pre-clinical years of training as a
medical student (Track 2). It is very difficult to arrange an individual Ph.D. partnership
when applying before starting medical school. Consequently, all applicants to Track 1 of
the MD/PhD partnership are required to co-apply at least one institutional NIH Graduate
Partnership Program.
When and how do I apply for the NIH intramural MD/PHD partnership training? If
you are not currently enrolled in medical school, you should apply for the MD/PhD
partnership in the same admissions cycle as you are applying for traditional MD/PhD
programs and GPP training for. The deadline for MD/PhD track 1 and 2 applications is in
early January, with details available on our homepage. Deadlines for each NIH Ph.D.
program are posted on their web sites, which can be accessed from the list of
partnerships. The MD/PhD program application does NOT count against the limit of
three NIH graduate partnership programs to which you can apply. Oxford and Cambridge
count as ONE partnership as the program is jointly run.
If you are a medical student you should apply for track 2 of the MD/PhD partnership in
January of year you would like to start Ph.D. training. If you are a current GPP student
you should apply for internal ‘pre-review’ in the spring BEFORE applying for track 3.
This deadline is in late May or early June. Applications for track 3 training may be
submitted to most schools for deferred enrollment in medical school after completion of
the bulk of the Ph.D. research.
In all cases, to be eligible for funding through the partnership MSTP you must apply to
medical schools participating in the MSTP and apply for MD/PHD training even if you
are already enrolled or fully intending to do your Ph.D research at NIH. This is to give
you maximum flexibility and also to allow the medical school MSTP program to
independently consider your application. A significant portion of the costs of MD/PHD
training even for NIH partnership students is borne by the Medical School MD/PHD
training program. If you are accepted for M.D.-only training you can participate in the
program but will not be eligible for tuition and stipend benefits during medical school.
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Which Medical Schools participate in the program? All medical schools receiving
training funds from the NIGMS MSTP are eligible to participate to receive NIH
partnership MSTP funding. However, financial and programmatic constraints have
limited the participation of some schools. Please see the list of participating institutions
on our website for more information.
I am attending a Medical School that does not currently receive NIH MSTP funding.
Can I still participate in this program? If accepted into a GPP program, you can
participate in combined degree training activities and receive funding for Ph.D. Training.
There is currently no mechanism for distributing MSTP funding for the medical school
portion of the training to schools not receiving an MSTP grant. Loans and scholarships
for this may be available through your medical school, and some non-MSTP funded
MD/PhD programs have allowed students to do all or part of their PhD. research in the
intramural program of NIH. However, there are individual NIH fellowships that fund
both phases of MD/PhD training at any U.S. medical school. See our funding
opportunities page for more details on alternatives to the MSTP for medical school
funding of MD/PHD training.
I am a post-baccalaureate student doing research at NIH in the post-bac IRTA or techIRTA program. How should I apply for NIH intramural MD/PHD partnership
training? If you are not committed to the lab you are currently working in, then you
should apply to the MD/PhD training programs of your choice across the country, and
simultaneously apply to an NIH GPP for the Ph.D. training. You could return to your
current lab after the pre-clinical years of medical school. If you are committed to
finishing research training in the lab in which you are currently working before attending
medical school, you can pursue by applying to a GPP PhD program and simultaneously
or subsequently applying to track 3 of the MD/PhD partnership. See above for
comparison of these training pathways.
I am a medical student interested in switching to track 2 partnership MD/PhD training.
What should I do? You should apply to one of the NIH Institutional Partnerships or
arrange an Individual Partnership with a PhD program at your medical school and an NIH
investigator. Additionally if you want to be considered for NIH partnership funding on
your return to medical, you must apply to your MSTP program as an internal candidate.
Currently, all medical schools funded by the MSTP allow this, other than U.C.S.F., the
Cornell/Rockefeller/Sloan-Kettering tri-institutional program, and the University of
Pennsylvania (with the exception of students in the NIH-U.Penn immunology GPP).
I am in a traditional funded MD/PhD program at my medical school. Can I participate
in the NIH MSTP? Yes, if allowed by your Ph.D. program, you may be able to do all or
part of your Ph.D. research in an NIH lab and obtain your Ph.D. from the University
affiliated with your medical school as an individual partnership student. You can also
apply for one of the institutional NIH GPP programs with the Ph.D. obtained from
elsewhere. However, both these options must be discussed with your MD/PhD program
advisors ahead of time and written permission to apply for either of these options must be
obtained from the director of your MD/PhD program.
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I am a current NIH GPP Ph.D. student and want to go to medical school. What should
I do? If you intend to primarily practice medicine after graduating from medical school,
you should apply for M.D. training and not participate in the NIH intramural MD/PhD.
partnership program. If you intend to spend at least 50% of your time in a research setting
(basic or translational) you should apply for pre-review by the NIH intramural MD/PhD.
partnership in the spring before applying to MD/PhD programs under track 3 of the
MD/PhD partnership. Information about this application cycle is sent to all NIH graduate
students through the OITE Grad-L listserv each year. You must have at least one year of
Ph.D. training remaining and be in good academic standing in your GPP. During
interviews with representatives of the NIH intramural MD/PhD partnership you will
receive individual counseling about which schools would be most appropriate to apply to.
If you are declined support for MSTP funding by the NIH intramural partnership you are
free to re-apply to the MSTP partnership in a future year or apply to medical school for
MD training following your PhD without NIH financial support.
C) NIH Intramural MD/PhD Partnership Program features and policies
How many students are in the NIH Intramural MD/PhD Partnership? The first
students entered the program in 2001, and the MSTP funding portion of the partnership
was launched in 2006. As of 2010, there are 54 students in the NIH MD/PhD Partnership
attending 28 different medical schools. 38 students are funded for medical school through
the MSTP, and five have been awarded individual NIH training awards that fund their
training. Most students are in the NIH-Oxford-Cambridge Ph.D. program, with 10
students in individual Ph.D. partnerships with their medical schools, and one in the NIHKarolinska Ph.D. training program. We accept about four new students a year in Track 1
prior to beginning medical school, 2-4 students a year in track 2 from medical school, and
2-4 students currently in the GPP for track 3 where medical school training follows the
Ph.D.
What can I do to maintain ties to clinical medicine while I am in the research phase of
NIH Intramural MD/PhD Partnership training? GPP Students enrolled in combined
degree training will receive the enhanced curriculum offered to MD/PhD students at their
medical school, which include program retreats, coursework and seminars designed for
combined degree trainees, as well as modified clinical rotation requirements. The
program aims to provide bridges to clinical medicine and clinical investigation while
students are in the research phase of training at the NIH. See our web page on program
activities for more information on these opportunities. In addition we sponsor students
each year to travel to meetings such as the National MD/PHD student meeting in
Colorado and every other year we host a student symposium at NIH. See our web page
on student meetings and symposia for more information on these opportunities.
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Do I have to finish my Ph.D. before returning to or beginning medical school?
Like most MD/PhD programs we have found that it is very important to finish the
dissertation research before entering or returning to the busy environment of medical
school. Therefore we do require that our students submit their Ph.D. to their thesis
committee or readers before returning to medical school. With permission of the program
director, the oral defense can take place after returning to medical school. Research and
work on publications often continue after the Ph.D. defense.
What can I do to maintain ties to research during the medical school phase of my
training? In track 3 of the NIH intramural partnership program, at least four years may
pass after your PhD training where you would not be engaged in research full time. This
is not an optimal situation because your research skills may deteriorate due to lack of use.
To prevent this from occurring, we expect students in this training pathway to plan an
extension of their PhD research or a related project with a mentor at the medical school;
this arrangement would ideally involve participation on the part of your current PhD
mentors. When you are researching MSTP programs to which you are considering
applying, we strongly recommend you focus on those with suitable mentors and research
time built into the medical school curriculum.
What advising and career counseling will I receive in the NIH intramural MD/PhD
partnership program? In addition to the GPP and Medical School MD/PhD program
advisors, NIH MD/PhD partnership students will be assigned to a designated NIH faculty
member MD/PhD advisor for the length of their training. These advisors are all
experienced physician-scientists who serve on the steering committee of NIH intramural
MD/PhD partnership program. Students submit an individualized training plan in the first
year of their training and annual progress reports which are shared with their medical
school, graduate school and MD/PhD advisors.
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