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ADHD stands for attention deficit hyperactivity disorder it's a very big problem the current estimates are that 11% of children more than one out of ten meet the diagnosis for ADHD and there's been a remarkable growth in the number of adults who meet the diagnostic criteria the literature is that about half of children no longer meet the diagnosis by the time they're adults often there are remaining difficulties so they don't outgrow it as if they never had it but often they have considerable improvement that shows up in their educational and occupational success in this study we're interested in investigating the default mode Network and patients who had ADHD the default mode network are regions that have been known to be typically activated more during race and those religions are the medial prefrontal cortex the posterior cingulate lateral final cortices the default network is the first time we can have a neural system that reflects self-referential processing what's been found in typically developing people is we have the synchrony and your default mode network so when these regions go up the other regions go up in ADHD that's not the case and that's been identified in adults that's been identified in children but it hasn't been identified is people that have been diagnosed as children and then followed longitudinally and that's what's unique about our sample so these subjects came in we got structural scans diffusion-weighted scans and one of the scans we got was this resting state scanner so during that scan their job was just to lie as still as possible for six minutes and think of nothing in particular so in the room inner group the question was would their brain look like that people that resisted with their ADHD diagnosis and in adulthood or look like controlled and what they looked like was like controls like people that had never been diagnosed with a in other words it looks like the remitted ADHD somehow we're able to normalize our resting state functional connectivity to the PCC and attract the current clinical status it wasn't that the people that remitted were completely like controls in every way possible we also know at rest that there are these task-related networks these tests positive networks and we wanted to see the relationship between the test positive networks and the default mode network in our example so in control they show an anti correlation so when the default low network goes up the test positive network goes down and so what we wanted to identify was whether or not there is a similar kind of anti correlation in the room iterative and persistent group and what we found was this was not observed in the readers or in the persisting in other words that wasn't emitted and significantly less default mode Network anti correlations and regions like the dorsal lateral prefrontal cortex donessa jessa the developmental history of having ADHD does leave something impact that we can see in the brain and so so it's a little of both it's both some religions clinically but also some continuation from the chocolate history first of all it communicates that some significant number of individuals do improve in terms of clinical status the second thing is we hope that the convergence of different forms of evidence will help make people more confident about the diagnosis and treatment selection so this is a small step forward but we're hoping that convergence objective scientific information will start to help make it easier to see what was you know correct useful pathway to help a child