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did you know that when a woman becomes pregnant her blood contains met for babies DNA this means a blood sample from a pregnant woman can tell us the chance that her baby has certain health conditions like Down syndrome these types of conditions most often occur by chance and are not inherited most of the time we'll find that the chance the baby has one of these conditions is low but even if the chance is high we believe it's good to know this information about your pregnancy my name is Leanne it's important both to me and my entire team that you feel comfortable with the information you request from myriad in the next few minutes I'll go through some information about the Marriot prequel prenatal screen if you find yourself wanting more information than I cover in this video you can speak with your health care provider or contact us at myriad women's health com [Music] the myriad prequel prenatal screen can tell you the likelihood that your baby has certain chromosome alterations a chromosome is a large collection of information inside our cells which contains many pieces of DNA called genes I like to think of a chromosome like a cookbook and each gene is like a recipe within the cookbook our chromosomes contain thousands of genes or recipes that instruct our bodies how to grow develop and function the typical number of chromosomes in our cells is 46 23 from each parent our chromosomes are numbered from 1 to 22 in the final pair determines sex the most common chromosome alterations involve extra or missing pieces of information which can interfere with the body's typical development for example Down syndrome is a condition that occurs because of an extra copy of chromosome number 21 another condition called trisomy 18 occurs because of an extra copy of chromosome 18 chromosome alterations may cause physical or intellectual disability but the severity can vary depending on the alteration the entire list of conditions that can be included in the screen can be seen at myriad women's health calm your doctor may only test you for a subset of conditions on the myriad prequal prenatal screen so it's important to understand what's included in your specifics [Music] while most people will receive reassuring news some will get a positive result which means there's a greatly increased chance the pregnancy has a chromosome alteration while the myriad prequel prenatal screen is highly accurate it's important to understand that if you receive a positive result the next step typically involves confirming the result with a medical procedure such as chorionic villus sampling or amniocentesis if you test positive we encourage you to speak with a genetic counselor or your doctor about the next steps if you are interested in knowing the sex of your baby the myriad prequel prenatal screen can provide this information as I mentioned earlier the final pair of chromosomes determines sex women have two X chromosomes while men have one X chromosome and one Y chromosome the main reason to look at the sex chromosomes is because alterations in these chromosomes can cause certain health conditions just like alterations in any of our other chromosomes for example Turner syndrome is a condition that occurs because of the missing X chromosome again the entire list of conditions that can be included in the screen can be seen at myriad women's health com you should discuss with your doctor which conditions are included in your specific screen [Music] the myriad prequel prenatal screen is designed to detect conditions which typically occur by chance and does not screen for cystic fibrosis tay-sachs disease spinal muscular atrophy or other inherited conditions screening for inherited conditions is included in the myriad 4sight carrier screen which looks at your and your partner's DNA rather than your babies please see myriad women's health comm for details about the 4sight carrier screen the myriad prequel prenatal screen can only be performed on a blood sample during pregnancy it can be done as early as 10 weeks after the first day of your last period or eight weeks after conception while the myriad prequel prenatal screen is highly accurate it cannot eliminate the chance to have a baby with a chromosome alteration and any results you receive are only applicable to your current pregnancy the results do not apply to future pregnancies in general this screen is included with most insurance policies but coverage may depend on your personal and family history it's important to understand that the myriad prequel prenatal screen is one of many prenatal screening options available to you if you have specific questions or concerns you may wish to speak with your healthcare provider or a local genetic counselor about all of your options to find a local genetic counselor visit the National Society of genetic counselors at NSG Sea Org [Music]