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we are honored to have dr robert turner give today's lecture dr turner is currently a senior research advisor for synthetic molecular design and development at eli lilly he has a responsibility for creating and implementing drug product strategies across lilly's synthetic molecular drug product portfolio dr turnick has over 30 years of experience in formulation and development in manufacturing process scale up and tech transfer he has overseen the development of more than 40 pivotal clinical and commercial formulations he sets on lilly's pediatric steering committee and is actively engaged in both the u.s and european based pediatric product development consortium dr turnick is a pharmaceutical industry representative on the federal task force on research specific to pregnant women and lactating women through hhs in nichd please enjoy today's presentation welcome to the nih principles of clinical pharmacy course i'm dr robert turnick senior advisor for eli lillian company and it's my pleasure to talk to you today about drug formulation and delivery as disclosure i am an employee and shareholder of eli lilly and company so what is this lecture about today today we'd like to cover uh a number of topics around the key patient technical and business considerations when we're converting a drug substance into a medicine with real focus on drug product design and development so the learning objectives for today are um really around a review of some principles of human centered design that i find are really important in the broader context of drug product design and pharma as well as critical quality attributes um a short discussion on different modalities and then a lot of detail on some key attributes of drug substance product design drivers and routes of delivery which will really form the the basis of the talk and towards the end i'll touch very briefly on some pharmaceutical packaging labeling and device considerations as well as a few thoughts on alternative administration and special populations so as you can see it's quite an ambitious agenda that we have to get through today and so the real question is is is where do we start and i think it really starts with the patient and this concept of design so why design we can take lessons from orthogonal industries like the food industry or automotive industry where we see the impact of of design every day and and in the pharmaceutical industry you may ask yourself well why would design be as important when we're not talking about for example a consumer product and i think a lot of the reason goes back to just the evolution of health care in society the autonomy that patients have these days with regard to choice and and dictating their own treatment as well as the autonomy of physicians and health care providers so choice does become a matter of of a conscious decision and so if we look at for example i have on the the the image here around heinz right...
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