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in order to be a donor the potential donor has to be healthy they have to be blood type compatible they can't have liver disease obviously and they shouldn't have other medical conditions that would either make surgery high-risk or where the loss of a part of their liver might impede their own safety and well-being once they go through that evaluation they can serve as a liver donor the risk of liver donation is the risk of almost any major abdominal surgery the risk of dying is quite small but it is a present risk as it is with any operation there have been over 2,000 living donor procedures done in the United States and up to today we've had three donor deaths so the risk is clearly less than one in 500 but it is not without significant morbidity or illness this is a big operation and so patients have a large scar they can get leakage of bile or blood from that cut edge of the liver where it was removed they can get infections hernias and other problems that desire to do a safer operation for the donor is what led our program to start to try to do left lobe adult-to-adult liver transplant we've known it could be done when the donor was much larger than the recipient but we are trying to apply it more systematically in more size matched donor-recipient pairs because the left lobe operation is safer for the donor we can do it laparoscopically in many cases and by improving the safety and tolerability of this procedure we may make it applicable to more potential recipients and enable family members and ourselves to save more lives with transplantation the donor experience is generally a gratifying one how many of us in our lives will have a chance to save the life of someone we love we know that undergoing the living donor liver transplant reduces the risk of dying on the waiting list by over 50% so for most of them it is gratifying unfortunately they still do have to have a major operation and so they will have pain they will have a recovery period and they will be tired as their body devotes enormous amounts of energy and attention to regenerating the liver the liver is an amazing organ with enormous regenerative capacity I'm always taken by the fact that after we remove 60% of the liver the liver will return to normal function within four to six weeks we'll have 80% of its original size in that period of time now during those four to six weeks patients can feel a little wiped out and at the same time they may be dealing with a sick family member who had to have a liver transplant so it is not an easy decision that should be taken lightly by anybody but almost all of our donors at the end of the day say they're glad they did it because...